• On the involvement of BDNF signaling in memory reconsolidation

    In this review, we discuss recent reports supporting the involvement of BDNF signaling in reactivation-induced memory updating.
  • Influence of BRCA1 germline mutations in the somatic mutational burden of triple-negative breast cancer

    The data presented here indicate that in the absence of BRCA1 germline mutations, a higher number of driver mutations are required for tumor development and that different defective processes are operating in the tumorigenesis of hereditary and sporadic TNBC in young women....
  • Essential Saccharomyces cerevisiae genome instability suppressing genes identify potential human tumor suppressors

    Gross Chromosomal Rearrangements (GCRs) play an important role in human diseases, including cancer. Although most of the nonessential Genome Instability Suppressing (GIS) genes in Saccharomyces cerevisiae are known, the essential genes in which mutations can cause increased GCR rates are not well...
  • Identification and characterization of primordial germ cells in a vocal learning Neoaves species, the zebra finch

    Our findings demonstrate important differences in the PGCs of the zebra finch and advance the first stage of creating PGC-mediated germ-line transgenics of a vocal learning species.
  • Disentangling chemical and electrical effects of statusepilepticus-induced dentate gyrus abnormalities

    In rodents, status epilepticus (SE) triggered by chemoconvulsants can differently affect the proliferation and fate of adult-born dentate granule cells (DGCs). It is unknown whether abnormal neurogenesis results from intracellular signaling associated with drug-receptor interaction, paroxysmal activity, or both.
  • A distinct class of bursting neuronswith strong gamma synchronizationand stimulus selectivity in monkey V1

    We show that in awake monkey V1, there exists a distinct cell type (››30% of neurons) that has narrow-waveform (NW) action potentials and high spontaneous discharge rates and fires in high-frequency bursts. These neurons are more stimulus selective and phase locked to...
  • Vocal and locomotor coordination develops in association with the autonomic nervous system

    We found that vocalizations matured sooner than postural and locomotor skills, and that vocal-locomotor coordination improved with age and during elevated arousal levels. These results suggest that postural-locomotor maturity is not required for vocal development to occur, and that infants gradually improve...
  • Vocal state change through laryngeal development

    Our results emphasize the importance of embodied approaches to vocal development, where exploiting biomechanical consequences of changing material properties can simplify motor control, reducing the computational load on the developing brain.
  • Is perception the missing link between creativity, curiosity and schizotypy? Evidence from spontaneous eye-movements and responses to auditory oddball stimuli

    We further compared saliency maps finding that individuals high versus low in creativity and curiosity, respectively, exhibit differences in where they look. These findings may suggest a perception-based link between creativity and curiosity, but not schizotypy. Implications and limitations of these findings...
  • The impact of Ayahuasca on suicidality: results from a randomized controlled trial

    The findings suggest that ayahuasca may show potential as an intervention for suicidality. We highlight important limitations of the study, potential mechanisms, and future directions for research on ayahuasca as an intervention for suicidality.
  • Chrna2-OLM interneurons display different membrane properties and h-current magnitude depending on dorsoventral location

    Thus, our results highlight regional differences in membrane properties between dorsal and ventral OLM cells allowing this interneuron to differently participate in the generation of hippocampal theta rhythms depending on spatial location along the dorsoventral axis of the hippocampus.
  • Hippocampal CA1 and cortical interictal oscillations in the pilocarpine model of epilepsy

    Quantitative electroencephalogram analysis has been increasingly applied to study fine changes in brain oscillations in epilepsy. Here we aimed to evaluate interictal oscillations using pilocarpine model of epilepsy to identify changes in network synchronization.