Publications

  • On the boundary conditions of avoidance memory reconsolidation: An attractor network perspective

    05/15/2020
    In the present work, by adapting the model of Osan et al. (2011) to simulate the experimental protocols of Radiske et al. (2017), we show that such boundary condition is compatible with the dynamics of an attractor network that supports synaptic...
  • Long-term potentiation prevents ketamine-induced aberrant neurophysiological dynamics in the hippocampus-prefrontal cortex pathway in vivo

    04/29/2020
    Our results show that KET promotes an aberrant delta-high-gamma cross-frequency coupling in the PFC and an enhancement in HPC-PFC evoked responses. LTP induction prior to KET attenuates changes in synaptic efficiency and prevents the increase in cortical gamma amplitude comodulation.
  • Anxiety-like behavior induced by salicylate depends on age and can be prevented by a single dose of 5-MeO-DMT

    02/11/2020
    Here we investigate if the anxiogenic effect of salicylate is dependent on age and previous tinnitus experience. We also tested whether a single dose of DMT can prevent this effect.
  • On the involvement of BDNF signaling in memory reconsolidation

    11/20/2019
    In this review, we discuss recent reports supporting the involvement of BDNF signaling in reactivation-induced memory updating.
  • Influence of BRCA1 germline mutations in the somatic mutational burden of triple-negative breast cancer

    11/20/2019
    The data presented here indicate that in the absence of BRCA1 germline mutations, a higher number of driver mutations are required for tumor development and that different defective processes are operating in the tumorigenesis of hereditary and sporadic TNBC in young women....
  • Essential Saccharomyces cerevisiae genome instability suppressing genes identify potential human tumor suppressors

    11/20/2019
    Gross Chromosomal Rearrangements (GCRs) play an important role in human diseases, including cancer. Although most of the nonessential Genome Instability Suppressing (GIS) genes in Saccharomyces cerevisiae are known, the essential genes in which mutations can cause increased GCR rates are not well...
  • Identification and characterization of primordial germ cells in a vocal learning Neoaves species, the zebra finch

    11/20/2019
    Our findings demonstrate important differences in the PGCs of the zebra finch and advance the first stage of creating PGC-mediated germ-line transgenics of a vocal learning species.
  • Disentangling chemical and electrical effects of status epilepticus-induced dentate gyrus abnormalities

    11/20/2019
    In rodents, status epilepticus (SE) triggered by chemoconvulsants can differently affect the proliferation and fate of adult-born dentate granule cells (DGCs). It is unknown whether abnormal neurogenesis results from intracellular signaling associated with drug-receptor interaction, paroxysmal activity, or both.
  • A distinct class of bursting neurons with strong gamma synchronization and stimulus selectivity in monkey V1

    11/20/2019
    We show that in awake monkey V1, there exists a distinct cell type (››30% of neurons) that has narrow-waveform (NW) action potentials and high spontaneous discharge rates and fires in high-frequency bursts. These neurons are more stimulus selective and phase locked to...
  • Vocal and locomotor coordination develops in association with the autonomic nervous system

    11/19/2019
    We found that vocalizations matured sooner than postural and locomotor skills, and that vocal-locomotor coordination improved with age and during elevated arousal levels. These results suggest that postural-locomotor maturity is not required for vocal development to occur, and that infants gradually improve...
  • Vocal state change through laryngeal development

    11/19/2019
    Our results emphasize the importance of embodied approaches to vocal development, where exploiting biomechanical consequences of changing material properties can simplify motor control, reducing the computational load on the developing brain.
  • Is perception the missing link between creativity, curiosity and schizotypy? Evidence from spontaneous eye-movements and responses to auditory oddball stimuli

    11/19/2019
    We further compared saliency maps finding that individuals high versus low in creativity and curiosity, respectively, exhibit differences in where they look. These findings may suggest a perception-based link between creativity and curiosity, but not schizotypy. Implications and limitations of these findings...